11. December 2017
Use of a self-microemulsifying drug delivery system (SMEDDS) is widely known as one of the most effective approaches to overcome problems associated with low solubility and poor oral absorption of water-insoluble drugs. Previously, we have demonstrated that a super saturable SMEDDS (SuSMEDDS) greatly contributed to enhanced dissolution and oral absorption of valsartan (VST), a drug with poor solubility in water ...
09. October 2016
ABSTRACT The purpose of the study was to prepare orally disintegrating tablets (ODTs) of mosapride citrate for dogs with fast disintegration and low cost. The ODTs were developed by varying the components and the ratio of excipients. A direct compression method was used. The properties of the ODTs, including hardness, friability, active ingredient content, and in vitro disintegration time, were investigated, and an economic analysis of the formulations was performed. For all formulations,...
18. April 2016
In the present study an attempt has been made to evaluate Ocimum bascilium mucilage coprocessed with Mannitol as a novel super disintegrant. Coprocessed excipients were prepared by solvent evaporation method and evaluated in the formulation of mouth dissolving tablets of Terbutaline sulphate. Formulated mouth dissolving tablets were characterised for physicochemical parameters like hardness, friability, weight variation, disintegration time, drug content and in vitro drug release behaviour. The...