Tricalcium citrate (TCC) was characterized as a tableting excipient for direct compression (DC) and dry granulation (DG). SIGNIFICANCE: Brittle materials usually lead to tablets of inferior mechanical strength compared to plastic deforming materials. A brittle material exhibiting a high tabletability with the ability to retain that behaviour during recompression would represent a valuable alternative to the commonly used microcrystalline cellulose (MCC). METHODS: Tablets of TCC and other common...
There is considerable interest in formulations with high active pharmaceutical ingredient (API) load, for reasons including lower patient tablet burden and therefore, potentially improved patient adherence. This remains a challenge not least because most APIs are poor flowing.
Dow Pharma Solutions demonstrated its commitment to advancing the pharmaceutical sciences by exhibiting research findings in a range of posters at the 2017 AAPS show in San Diego, CA. Please find below links to copies of our presented posters.
ARMOR PHARMA™ lactose monohydrate 350M is a fine milled powder of α-lactose monohydrate.
Higly compressible, this grade is mostly intended to be used in tablets formulation by Wet or Dry granulation.
We aimed to investigate the feasibility of our previously proposed method for improving the properties of dry granules by pre-coating of active pharmaceutical ingredients (API) with a submicron-sized binder before conventional roller compaction in lab-scale production.