Silica nanoparticles: Preparation, characterization and in vitro/in vivo biodistribution studies

The aim of the present study was to characterize and evaluate both in vitro, by microscopy techniques, and in vivo, by scintigraphic imaging, the biodistribution of silica nanostructures derivatives (Cy5.5 conjugated SNPs and 99mTc radiolabelled SNPs) to be applied as radiotracers in biomedicine.


Received 20 August 2014, Revised 9 January 2015, Accepted 2 February 2015, Available online 11 February 2015

http://www.sciencedirect.com/science/article/pii/S0928098715000524