Nano and Microparticulate Chitosan Based System for Formulation of Carvedilol Rapid Melt Tablet
In the present study rapid melt tablets (RMT’s) of carvedilol were prepared by using ionotropic-gelated chitosan nanoparticles using a spray-drying method. Carvedilol is
beta-adrenergic antagonist and its oral bioavailability is about 25-35% because of first pass metabolism.
beta-adrenergic antagonist and its oral bioavailability is about 25-35% because of first pass metabolism.