Soluplus as an effective absorption enhancer of poorly soluble drugs in vitro and in vivo
Michael Linn a, Eva-Maria Collnot a,b,⇑, Dejan Djuric c, Katja Hempel d, Eric Fabian d, Karl Kolter c,
Claus-Michael Lehr a,b
a Biopharmaceutics and Pharmaceutical Technology, Saarland University, 66123 Saarbrücken, Germany
b Helmholtz-Institute for Pharmaceutical Research Saarland (HIPS), Dept. of Drug Delivery (DDEL), Saarland University, Campus A 4 1, 66123 Saarbrücken, Germany
c BASF SE, R&D Pharma Ingredients, 67063 Ludwigshafen, Germany
d BASF SE, Experimental Toxicology and Ecology, 67063 Ludwigshafen, Germany
Claus-Michael Lehr a,b
a Biopharmaceutics and Pharmaceutical Technology, Saarland University, 66123 Saarbrücken, Germany
b Helmholtz-Institute for Pharmaceutical Research Saarland (HIPS), Dept. of Drug Delivery (DDEL), Saarland University, Campus A 4 1, 66123 Saarbrücken, Germany
c BASF SE, R&D Pharma Ingredients, 67063 Ludwigshafen, Germany
d BASF SE, Experimental Toxicology and Ecology, 67063 Ludwigshafen, Germany