The impact of hot-melt extrusion on the tableting behaviour of polyvinyl alcohol

There is evidence that processing techniques like hot-melt extrusion (HME) could alter the mechanical properties of pharmaceuticals, which may impede further processability (e.g. tableting). The purpose of this study was to evaluate if HME has an impact on the tableting behavior of polyvinyl alcohol (PVA) – formulations.

More