03. March 2016

    Enhancing the Stability of a Famotidine Tablet Formulation through Use of Starch 1500®

    Purpose

    To evaluate the influence of Starch 1500®  partially pregelatinized maize starch on the physical and chemical stability of formulations containing the moisture sensitive active, famotidine which has a well characterized degradation pathway due to hydrolysis.

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    Enhancing the Stability of a Famotidine Tablet Formulation through Use ofStarch 1500®
    Gus LaBella1 and Kevin Hughes2
    1Colorcon, Inc., Harleysville, PA USA; 2Colorcon, Inc., Dartford, UK
    AAPS - Poster Reprint 2015
    pr_aaps_s_326_fam_starch.pdf
    Adobe Acrobat Document 302.6 KB
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    Tags: excipient, colorcon, starch, AAPS, stability, famotidine, mar2016, 1500