Novel doped calcium phosphate-PMMA bone cement composites as levofloxacin delivery systems - Abstract

Highlights

•Novel BC composites with improved mechanical integrity.

•Sustained in vitro release of the antibiotic (levofloxacin) from the BC composites over an 8-week period.

•Levofloxacin retained the antimicrobial activity against Staphylococcus aureus and Staphylococcus

 epidermidis over an 8-week in vitro release period.

•Biocompatible BC composites.

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