Juvenile Animal Testing of Hydroxypropyl-β-Cyclodextrin in Support of Pediatric Drug Development - Abstract

Hydroxypropyl-β-cyclodextrin (HP-β-CD) is being explored as excipient for administration of poorly soluble NCE's in pediatrics. In support of pharmaceutical development, non-clinical studies were performed to investigate whether oral and intravenous administration of HP-β-CD showed a different response in juvenile rats versus adult rats.

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